Loss of Heterozygosity on Chromosome 19 in Secondary Glioblastomas

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چکیده

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منابع مشابه

Loss of heterozygosity on chromosome 10q in glioblastomas, and its association with other genetic alterations and survival in Indian patients.

BACKGROUND Glioblastoma multiforme (GBM) is the most common malignant central nervous system neoplasm. Loss of heterozygosity (LOH) on chromosome 10q in these tumors has been found to show variable association with prognosis. AIM To evaluate LOH 10q status in cases of GBM, and to correlate these results with patient characteristics, other genetic alterations, and survival. MATERIAL AND METH...

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Loss of heterozygosity on chromosome 1q in human breast cancer.

Cytogenetic markers involving the long arm of chromosome 1 are the most frequently observed karyotypic changes seen in breast cancer. Based on cytogenetic data, we have used polymorphic DNA markers to search for allelic losses at this chromosome region among 48 breast carcinomas. For SPTA1, allelic losses were seen in 6 of 26 (23%) informative carcinomas, while 3 of 13 (23%) and 5 of 19 (26%) i...

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Loss of heterozygosity on chromosome 11 q in breast cancer.

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ژورنال

عنوان ژورنال: Journal of Neuropathology & Experimental Neurology

سال: 2000

ISSN: 0022-3069,1554-6578

DOI: 10.1093/jnen/59.6.539